Research Highlights

Latorre E, Tebaldi T, Viero G, Spartà AM, Quattrone A, Provenzani A. Downregulation of HuR as a new mechanism of doxorubicin resistance in breast cancer cells. Mol Cancer. 2012 Mar 21;11:13.
http://www.ncbi.nlm.nih.gov/pubmed/22436134

The quantitative analysis of microRNA-205 together with an extended panel of immunohistochemical markers can be used in subtyping unclassifiable lung cancers.
Barbareschi M, Cantaloni C, Del Vescovo V, Cavazza A, Monica V, Carella R, Rossi G, Morelli L, Cucino A, Silvestri M, Tirone G, Pelosi G, Graziano P, Papotti M, Dalla Palma P, Doglioni G, Denti MA Heterogeneity of large cell carcinoma of the lung: an immunophenotypic and miRNA based analysis. Am. J. Clin. Pathol. 2011 136:773-782.
http://www.ncbi.nlm.nih.gov/pubmed/22031317

Martini L and Mansy SS (2011) Cell-like Systems with Riboswitch Controlled Gene Expression. Chem Commun 47, 10734-10736.
http://www.ncbi.nlm.nih.gov/pubmed/21869957

Beltran H, Rickman DS, Park K, Chae SS, Sboner A, MacDonald TY, Wang Y, Sheikh KL, Terry S, Tagawa ST, Dhir R, Nelson JB, de la Taille A, Allory Y, Gerstein MB, Perner S, Pienta KJ, Chinnaiyan AM, Wang Y, Collins CC, Gleave ME, Demichelis F, Nanus DM, Rubin MA. Molecular Characterization of Neuroendocrine Prostate Cancer and Identification of New Drug Targets. Cancer Discovery. 2011 Nov;1(6): 487-495.
http://www.ncbi.nlm.nih.gov/pubmed/22389870

A review on the complexity of prostate cancer.
Barbieri CE, Demichelis F, Rubin MA. Molecular genetics of prostate cancer: emerging appreciation of genetic complexity. Histopathology. 2012 Jan;60(1):187-98.
http://www.ncbi.nlm.nih.gov/pubmed/22212086

A technical note on the analysis of gene expression in specific regions of the central nervous system.
Messina A., Dunleavy M., Sgadò P., Adami V., Bozzi Y., Casarosa S. (2012) Region-specific gene expression in adult mouse CNS tissues. Leica Science Lab website.
http://www.leica-microsystems.com/science-lab/laser-microdissection/region-specific-gene-expression-in-adult-mouse-cns-tissues/

A review on the neurodevelopmental basis of epilepsy.
Epilepsy as a neurodevelopmental disorder Bozzi Y, Casarosa S, Caleo M. Frontiers in Molecular Psychiatry, in press.

Vidalino L, Monti L, Haase A, Moro A, Acquati F, Taramelli R and Macchi P.
Intracellular trafficking of RNASET2, a novel component of P-bodies.
Biology of the Cell. 2012 Jan;104(1):13-21.
http://www.ncbi.nlm.nih.gov/pubmed/22188480

Acquati F, Bertilaccio S, Grimaldi A, Monti L, Cinquetti R, Bonetti P, Lualdi M, Vidalino L, Fabbri M, Sacco MG, van Rooijen N, Campomenosi P, Vigetti D, Passi A, Riva C, Capella C, Sanvito F, Doglioni C, Gribaldo L, Macchi P, Sica A, Noonan DM, Ghia P, Taramelli R.
Microenvironmental control of malignancy exerted by RNASET2, a widely conserved extracellular RNase.
Proc Natl Acad Sci U S A. 2011 Jan 18;108(3):1104-9.
http://www.ncbi.nlm.nih.gov/pubmed/21189302

Alessandro Quattrone, Ralf Dahm and Paolo Macchi
SUBCELLULAR RNA LOCALIZATION AND TRANSLATIONAL CONTROL: Mechanisms and Biological Significance in theVertebrate Nervous System.
In RNA Binding Proteins, edited by Lorkovic Zdravko.
©2011 Landes Bioscience and Springer Science.

Ooi WF, Re A, Sidarovich V, Canella V, Arseni N, Adami V, Guarguaglini G, Giubettini M, Scaruffi P, Stigliani S, Lavia P, Tonini GP, Quattrone A.
Segmental chromosome aberrations converge on overexpression of mitotic spindle regulatory genes in high-risk neuroblastoma.
Genes Chromosomes Cancer. 2012 Feb 15. doi: 10.1002/gcc.21940. [Epub ahead of print] PubMed PMID: 22337647

Dassi E, Malossini A, Re A, Mazza T, Tebaldi T, Caputi L, Quattrone A.
AURA: Atlas of UTR Regulatory Activity.
Bioinformatics. 2012 Jan 1;28(1):142-4. Epub 2011 Nov 4. PubMed PMID: 22057158