Method to identify intermediates

Department/Centre: Department of  Physiscs / CIBIO - Department of Cellular, Computational and Integrative Biology
Inventors: Emiliano Biasini (UniTrento/Telethon), Pietro Faccioli  (UniTrento/INFN)
Field of use: Computational prediction and experimental exploitation of relevant intermediate states in the folding process of virtually any protein, with direct relevance for the entire field of drug discovery
Keywords: Protein Inactivation, Folded Intermediate Targeting
Bibliographical data: application number: 102018000007535 (Italian filing); priority date: 26/07/2018, CT/IB2019/056371 (PCT filing)
Assignees: Università di Trento, INFN, Telethon
Availability: available for license or assignment

Description

The invention consists in innovative in silico approaches, which allow to computationally predict relevant intermediate states in the folding process of a protein. These technologies enable to drastically lower the computational cost of simulating protein folding pathways with atomic-level resolution, leading to the identification of protein folding intermediate.

Ocular dominance measurement device

Department/Centre: CIMeC - Center for Mind/Brain Sciences
Inventors: Uri Hasson (UniTrento), Giuseppe Notaro (UniTrento), Valeria D'Andrea (ora Fondazione Bruno Kessler)
Field of use: security applications that use biometric features; customization of VR environments to reduce sickness; clinical or fitness test (i.e for pilots)
Keywords: ocular dominance; biometric; eye test; fitness test
Bibliographical data: application number: 102020000022120 (Italian filing); priority date: 18/09/2020
Assignees: Università di Trento
Availability: available for license or assignment

Description

This invention concerns a method to measure ocular dominance using a drawing device, a computer and computer screen. The apparatus is simple to setup and the measure is robust and it is obtained quickly.

Device for determining the mechanical properties of nanomaterials and relative method

Department/Centre: Department of Civil, Environmental and Mechanical engineering
Inventors: Nicola Pugno (UniTrento), Maria Pantano (UniTrento), Giorgio Speranza (Fondazione Bruno Kessler) 
Fields of use: bio-inspired nanomechanics, new materials with high performance characteristics, mechanical properties of nanomaterials, mechanical characterization of monoatomic materials and ultra-thin films
Keywords: nanomaterials, mechanical properties, traction tests
Bibliographical data: application number: 102017000108535 (italian filing); priority date: 28/09/2017
Assignees: Università di Trento
Availability: available for license or assignment

Description

This invention relates to an innovative setup to perform tensile tests on nanomaterials, such as microfibers and ultra-thin films. The sample  to be tested is anchored to a substrate, which is mechanically connected on one side to an actuator and on the other side to a sensor. The substrate has a pre-notch and, before the start of the test, it is broken in two facing blocks that provide the sensor and the actuator with the possibility of a relative movement.